Producing consistent paraffin sections requires more than simply setting the required section thickness on a microtome. The condition of the tissue block, cutting edge, microtome setup, sectioning technique and flotation […]
Bright Instruments is proud to be supporting the ESMS Mohs Course 2026, taking place on 11–12 September 2026 in London, with two brand-new OTF7050 cryostats for the course’s hands-on practical […]
Summary: Cryostats are used when laboratories need to prepare frozen tissue sections quickly while preserving biological structures that may be altered during conventional tissue processing. They play a vital role […]
Summary: Summary: Choosing the right rotary microtome is about more than comparing specifications. Laboratories should consider section quality, ease of operation, servicing support, ergonomics and long-term reliability to ensure the […]
Summary: Both sledge microtomes and rotary microtomes are designed to prepare tissue sections for microscopic analysis, but they are typically used for different specimen types and laboratory applications. In general: […]
Summary: For many laboratories, the Leica CM1950 has become the familiar default choice for frozen sectioning. However, more hospitals, universities and pathology laboratories are now comparing alternative cryostat systems side […]
Laboratories working with tissue sectioning often compare microtomes and cryostats when selecting the right equipment for their workflow. While both systems are designed to produce thin tissue sections for analysis, […]
Optimising temperature is the most effective way to improve frozen section quality across clinical and research settings. Different tissues behave differently under the blade, and their ideal temperature ranges vary […]
Temperature instability is the most common cause of artefacts in frozen sections. Even when technique, blade condition and embedding are well controlled, a small deviation in temperature can alter tissue […]
Cryosectioning is one of the most technique-sensitive steps in frozen histology, pathology and research processes. Despite the range of factors that influence section quality, temperature remains the single most decisive […]
Common Errors in Tissue Sectioning and Their Impact on Section Quality Sectioning is a deceptively delicate process. Every pathology, histology and research lab knows the pressure of producing perfect sections […]
Contact us for any enquiries. Whether you’re looking for a new cryostat, microtome or rapid freeze unit, need spares or servicing, or are interested in becoming a Bright distributor, our team is here to support you.
